2019 Nian 5 Yue 24- Ri , Chinese Academy of Agricultural Sciences research progress briefing announced the "African swine fever prevention and control research program" . After the occurrence of African swine fever epidemic, the Chinese Academy of Agricultural Sciences took African swine fever prevention and control as a major scientific research task to serve the national strategic needs, gathered superior resources, and set up the African swine fever prevention and control technology research project group at the first time to Harbin Veterinary Research Institute. , Lanzhou Veterinary Research Institute, Beijing Animal Husbandry and Veterinary Research Institute, Shanghai Veterinary Research Institute, Lanzhou Animal Husbandry and Veterinary Medicine Research Institute, Feed Institute, etc. as member units, gather the capable teams to form key research teams, and provide stable support through scientific and technological innovation project funding to develop vaccines As a key point, day and night, day and night, urgently carry out joint scientific and technological research on vaccines, immunization mechanisms, diagnostic tests, disinfection and pest control technologies. At present, the African swine fever vaccine independently developed by the Harbin Veterinary Research Institute has achieved staged results, and laboratory research results have shown that it has good biological safety and immune protection effects.
The details are as follows:
Major demand
1 . African swine fever passed to China's pig industry caused extremely serious threat. China is the world's largest country in pork consumption and pig breeding. The annual production of pigs is about 700 million. The output value of the pig breeding industry accounts for 18% of the total agricultural output value , and pork consumption accounts for 62% of the total meat consumption . African swine fever is the number one killer in the pig industry. There are no vaccines and no drugs to prevent and treat it. According to the epidemic characteristics of African swine fever globally and the current status of pig breeding in China, the epidemic situation will further expand in my country and will exist for a long time. The continued occurrence of African swine fever will have a devastating impact on my country's hog breeding industry, seriously affecting my country's food and nutrition security, winning the tough battle of poverty alleviation in rural areas, and the stable development of the economy and society.
2 . The lack of maturity, supporting the comprehensive prevention and control technology system. At present, the source of the epidemic situation of African swine fever in China and its prevalence in China are still unclear. It can only be controlled by comprehensive measures such as culling and disinfection. The main reason for this result is that China currently lacks the actual production conditions suitable for the country. , A mature and complete integrated prevention and control technology system, as well as diagnostic technical standards and effective and reliable vaccines, these have brought great difficulties to the prevention and control of African swine fever. Therefore, there is an urgent need to combine existing scientific research forces, strengthen joint research, develop high-throughput and rapid detection technology products, develop high-efficiency disinfection and pest control technology products, break through the bottleneck of African swine fever vaccine research as soon as possible, and create safe and effective vaccines for prevention and treatment. The long-term prevention and control of the African swine fever epidemic in China has played a key scientific and technological support role.
The overall goal
Focusing on the current technical requirements for effective prevention and control of African swine fever epidemic, we will carry out scientific and technological research from three aspects: early diagnosis of the source of the epidemic, effective cut-off of the epidemic transmission chain, and construction of the epidemic protection wall. And pest control technology products, create African swine fever prevention and control vaccines, and provide scientific and technological support for the effective control and purification of African swine fever epidemic in China.
Overall technical route
( 1 ) R&D of technical products that confirm the source of the epidemic diagnosis as soon as possible to form an integrated solution for on-site diagnosis ;
( 2 ) Develop efficient and environmentally friendly disinfection technology products and insecticide technology products to form a solution to effectively kill African swine fever wild vectors ;
( 3 ) Create technical products for constructing epidemic protection walls to provide technical support for regional prevention or purification of African swine fever. Forming a green and efficient comprehensive technical system for prevention and control of African swine fever.
Research content
( 1 ) Study on the immunosuppressive mechanism of African swine fever virus
1 . Mechanism innate immune response suppression of African swine fever virus
2 . Reaction mechanisms of the African swine fever virus interfere with the host inflammatory cells
3 . Mechanism of host immune tolerance caused by African swine fever virus
( 2 ) Diagnosis and testing technology and product development
1 . Our ASFV molecular characteristics of a pandemic strain
2 . R & D ASFV diagnostic technologies and related products
( 3 ) Disinfection technology and product development
1 . Efficient, environmentally friendly veterinary medicine research and chlorine dioxide disinfection of the environment
2 . Veterinary quaternary ammonium compound disinfectant foam developed with animals
3 . Hypochlorite disinfectant veterinary research and slightly acidic
4 . Veterinary composite developed potassium sulphate through disinfectant
5 . Evaluation and application-specific disinfectant African swine fever virus
( 4 ) Pest control technology and product development
1 . Media biota surveys, studies and biological characteristics of artificial culture techniques
2 . Biological agents to kill and drug screening technology
3 . Technology development and application of biological control
4 . Pesticidal application and technology integration demonstration
( 5 ) Creation of gene deletion vaccine
( 6 ) Creation of live carrier vaccine
Lead unit: Ha Beast Research
Participants: Lan Veterinary, Shanghai Veterinary, Lanmu Pharmaceutical, Beijing Animal Husbandry, Feed
Post time: Jun-21-2019
