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Doxycycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Doxycycline is also active against Chlamydia, Mycoplasma and Rickettsia spp. The action of doxycycline is based on inhibition of bacterial protein synthesis. Doxycycline has a great affinity to the lungs and is therefore especially useful for treatment of bacterial respiratory infections.

Indications

Gastrointestinal and respiratory infections caused by doxycycline sensitive micro-organisms like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.

Contra-indications

Hypersensitivity to tetracyclines.

Administration to animals of a seriously impaired liver function.

Concurrent administration with penicillines, cephalosporines, quinolones and cycloserine.

Administration to animals with an active microbial digestion.

Side Effects

Discoloration of teeth in young animals.

Hypersensitivity reactions.

Dosage

For oral administration:

Calves, goats and sheep : Twice daily 1 gram per 100 kg body weight for 3 – 5 days.

Poultry and swine : 100 gram per 500 – 1000 litre drinking water for 3 – 5 days.

Note: for pre-ruminant calves, lambs and kids only.

Withdrawal Times

- For meat:

Calves, goats and sheep : 14 days.

Swine : 8 days.

Poultry : 7 days.

For Veterinary UseOnly , Keep out of reach of children