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Chinese wholesale Albendazole Bolus Tablet - Niclosamide Bolus 1250 mg – Lihua

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Chinese wholesale Albendazole Bolus Tablet - Niclosamide Bolus 1250 mg – Lihua Detail:

Niclosamide Bolus inhibits phosphorylation in the mitochondria of cestodes. Both in vitro and in vivo, the scolex and proximal segments are killed on contact with the drug. The loosened scolex may be digested in the intestine; hence, it may be impossible to identify the scolex in the faeces. Niclosamide Bolus is taenicidal in action and eliminates not only the segments but also scolex.

Niclosamide Bolus activity against the worms appears to be due to inhibition of mitochondrial oxidative phosphorylation; anaerobic ATP production is also affected.

The cestocidal activity of Niclosamide Bolus is due to the inhibition of absorbtion of glucose by the tapeworm and to the uncoupling of the oxidative phosphorylation process in the mitochondria of cestodes. The accumulated lactic acid resulting from the blocking of Krebs cycle kills the worms.

Indications

Niclosamide Bolus is indicated in both tapeworm infestation of Livestock, Poultry, Dogs and Cats and also in immature paramphistomiasis (Amphistomiasis) of Cattle, Sheep and Goats.

Tapeworms

Cattle, Sheep Goats and Deer: Moniezia Species Thysanosoma (Fringed Tape worms)

Dogs: Dipylidium Caninum, Taenia Pisiformis T. hydatigena and T. taeniaeformis.

Horses: Anoplocephalid infections

Poultry: Raillietina and Davainea

Amphistomiasis: (Immature Paramphistomes)

In cattle and Sheep, Rumen flukes (Paramphistomum species) is very common. Whereas the adult flukes attached to the rumen wall could be of little significance, the immature ones are seriously pathogenic causing heavy damage and mortality while migrating in the duodenal wall.

Animals showing symptoms of severe anorexia, increased intake of water, and watery fetid diarrhoea should be suspected for amphistomiasis and immediately treated with Niclosamide Bolus to prevent death and loss of production since Niclosamide Bolus provides consistently very high efficacy against the immature flukes.

Composition

Each uncoated bolus contains:

Niclosamide I.P. 1.0 gm

Administration and dosage

Niclosamide Bolus in feed or as such.

Against Tapeworms

Cattle, Sheep and Horses: 1 gm bolus for 20 kg body weight

Dogs and Cats: 1 gm bolus for 10 kg body weight

Poultry: 1 gm bolus for 5 adult birds

(Approximately 175 mg per kg body weight)

Against Amphistomes

Cattle & Sheep: Higher dosage at the rate of 1.0 gm bolus / 10 kg body weight.

Safety: Niclosamide bolus has a wide margin of safety. Overdosing of Niclosamide upto 40 times in sheep and cattle have been found to be non-toxic. In Dogs and cats, twice the recommended dosage causes no ill effects except softness of the faeces. Niclosamide bolus can safely be used in all phases of pregnancy and in debilitated subjects without adverse effects


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We now have our own gross sales team, style and design workforce, technical crew, QC workforce and package group. We now have strict quality manage procedures for each system. Also, all of our workers are experienced in printing industry for Chinese wholesale Albendazole Bolus Tablet - Niclosamide Bolus 1250 mg – Lihua , The product will supply to all over the world, such as: Russia, Canberra, Kenya, We also have the strong ability of integration to supply our best service, and plan to build the warehouse in the different countries around the world, that will probably be more conveniently to service our customers.
  • The supplier cooperation attitude is very good, encountered various problems, always willing to cooperate with us, to us as the real God.
    5 Stars By Jenny from Czech republic - 2018.11.28 16:25
    A nice supplier in this industry, after a detail and careful discussion, we reached a consensus agreement. Hope that we cooperate smoothly.
    5 Stars By Diego from Mexico - 2018.10.09 19:07
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